اثربخشی شناخت درمانی مبتنی بر ذهن آگاهی بر افسردگی و سطوح سرمی کورتیزول در زنان مبتلا به سرطان پستان و زنان افسرده

نوع مقاله : مقاله پژوهشی

نویسندگان

1 Ph.D. student, Department of Clinical Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.

2 Assistant professor, Department of Clinical of Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.

3 Professor, Department of Radiology, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Associate Professor Department of physiology, Shiraz Branch, Faculty of Science, Zand Institute of Higher Education, Shiraz, Iran.

چکیده

مقدمه: این مطالعه با هدف بررسی اثربخشی شناخت درمانی مبتنی بر ذهن آگاهی بر افسردگی و سطوح سرمی کورتیزول در زنان مبتلا به سرطان پستان و زنان افسرده انجام شد.
روش کار: در این کارآزمایی بالینی، 30 زن مبتلا به سرطان پستان مراجعه کننده به بیمارستان امید مشهد و 30 زن مبتلا به افسردگی مراجعه کننده به کلینیک های مشاوره مشهد در سال 2021-2020 به روش نمونه گیری در دسترس انتخاب و به صورت تصادفی به چهار گروه مساوی (2 گروه آزمون و 2 گروه شاهد)تقسیم شدند. گروه های آزمون طی هشت جلسه 90 تا 120 دقیقه ای در هفته درمان شناختی مبتنی بر ذهن آگاهی دریافت کردند، در حالی که گروه شاهد هیچ مداخله ای دریافت نکرد. ابزار تحقیق شامل پرسشنامه افسردگی (BDI-II) و نمونه خون برای ارزیابی سطوح کورتیزول بود. داده ها با استفاده از آمار توصیفی و تحلیل کوواریانس تحلیل شدند.
یافته‌ها: نتایج افراد افسرده نشان داد که شناخت درمانی مبتنی بر ذهن آگاهی در کاهش افسردگی و سطوح سرمی کورتیزول در محدوده طبیعی آزمایشگاهی مؤثر است (001/0P<). علاوه بر این، یافته‌های زنان مبتلا به سرطان پستان نشان داد که درمان، افسردگی را کاهش داده و کورتیزول سرم را از سطوح پایین تا متوسط ​​در محدوده نرمال آزمایشگاهی افزایش می‌دهد (001/0P<).
نتیجه‌گیری: شناخت درمانی مبتنی بر ذهن آگاهی می‌تواند علاوه بر بهبود علائم روان‌شناختی در افراد افسرده و بیماران سرطانی، در مکانیسم‌های عصبی زیستی نیز مؤثر باشد.

کلیدواژه‌ها


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