Fundamentals of Mental Health

Fundamentals of Mental Health

Misophonia and psychiatric comorbidities in patients referred to psychiatric clinic

Document Type : Research Paper

Authors
1 Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran. Department of Psychiatry, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
2 Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
3 Payam-e- Nour University, Tehran, Iran.
4 Department of Community Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
10.22038/jfmh.2025.87673.3317
Abstract
Introduction: Misophonia is a type of neurophysiological-behavioral phenomenon characterized by increased stimulation of the autonomic nervous system. The affected people experience emotional distress in response to sounds with specific patterns. This study investigates the frequency of misophonia and its related factors in the patients with a history of hospitalization due to psychiatric disorders.
Materials and Methods: This randomized descriptive study was performed on 291 patients, using a demographic and psychiatric history checklist and Misophonia Questionnaire (MQ). The descriptive and regression analysis statistical methods were employed to analyze the data.
Results: The MQ was completed for 213 patients including 41.3% men and 58.7% women. Nineteen% of the patients had hatred of some sounds out of whom 9% were diagnosed with Misophonia Syndrome (MS) and 10% suffered from SubSyndromal Misophonia (SSM). Among the misophonic patients, the most common annoying sound was others’ eating sound (36.8%) and in 53% of them, the reaction to the aversive sound was anger. There was a significant relationship between suffering from MS and marital status (P= 0.004), the type of psychiatric disorder (P< 0.001) and personality disorder (P< 0.001), as well as between SSM and gender (P= 0.02), education (P= 0.04), marital status (P= 0.001) and the type of psychiatric disorder (P< 0.001).
Conclusion: The prevalence of MS and SSM in patients with severe psychiatric disorders is noteworthy. Due to the distressing effect of misophonia on patients, it is necessary to pay attention to it in the diagnostic examination and treatment.
Keywords

1.                    Jastreboff MM, Jastreboff PJ. Components of decreased sound tolerance: Hyperacusis,
misophonia, phonophobia. ITHS News Lett 2001; 2(5-7): 1-5.
2.                   Jastreboff MM, Jastreboff PJ. Decreased sound tolerance and tinnitus retraining therapy
(TRT). Aust N Z J Audiology 2002; 24(2): 74.
3.                   Jastreboff PJ. Phantom auditory perception (tinnitus): Mechanisms of generation and perception. Neurosci Res 1990; 8(4): 221-54.
4.                   Jastreboff PJ, Gray WC, Gold SL. Neurophysiological approach to tinnitus patients. Am J Otol 1996; 17(2): 236-40.
5.                   Jastreboff PJ, Jastreboff MM. Treatments for decreased sound tolerance (hyperacusis and misophonia). Semin Hear 2014; 35(02): 105-120.
6.                   Brout JJ, Edelstein M, Erfanian M, Mannino M, Miller LJ, Rouw R, et al. Investigating misophonia: A review of the empirical literature, clinical implications, and a research agenda. Front Neurosci 2018; 7(12): 36.
7.                   Edelstein M, Brang D, Rouw R, Ramachandran VS. Misophonia: Physiological investigations and case descriptions. Front Hum Neurosci 2013; 25(7): 296.
8.                   Schröder A, van Diepen R, Mazaheri A, Petropoulos-Petalas D, Soto de Amesti V, Vulink N, et al. Diminished n1 auditory evoked potentials to oddball stimuli in misophonia patients. Front Behav Neurosci 2014; 9(8):123.
9.                   Wu MS, Lewin AB, Murphy TK, Storch EA. Misophonia: Incidence, phenomenology, and clinical correlates in an undergraduate student sample. J Clin Psychol 2014; 70(10): 994-1007.
10.                Kumar S, Tansley-Hancock O, Sedley W, Winston JS, Callaghan MF, Allen M, et al. The brain basis for misophonia. Curr Biol 2017; 27(4): 527-33.
11.                Sullivan JC, Miller LJ, Nielsen DM, Schoen SA. The presence of migraines and its association with sensory hyperreactivity and anxiety symptomatology in children with autism spectrum disorder. Autism 2014; 18(6): 743-7.
12.                Ben-Sasson A, Carter AS, Briggs-Gowan MJ. Sensory over-responsivity in elementary school: Prevalence and social-emotional correlates. J Abnorm Child Psychol 2009; 37(5): 705-16
13.                Rosenthal MZ, Neacsiu AD, Geiger PJ, Fang C, Ahn R, Larrauri J. Emotional reactivity to
personally-relevant and standardized sounds in borderline personality disorder. Cognit
Ther Res 2016; 40(3): 314-27.
14.                Cabranes JA, Ancín I, Santos JL, Sánchez-Morla E, García-Jiménez MA, Rodríguez-Moya L, et al. P50 sensory gating is a trait marker of the bipolar spectrum. Eur Neuropsychopharmacol 2013; 23(7): 721-7.
15.                Stansfeld SA, Clark CR, Jenkins LM, Tarnopolsky A. Sensitivity to noise in a community sample: I. Measurement of psychiatric disorder and personality. Psychol Med 1985; 15(2): 243-54.
16.                Mehrabizadeh Honarmand M, Roushani K. [Investigation of psychometric properties of misophonia questionnaire]. Shefaye Khatam 2019; 7(2): 13-22. (Persian)
17.                Quek TC, Ho CS, Choo CC, Nguyen LH, Tran BX, Ho RC. Misophonia in Singaporean psychiatric patients: A cross-sectional study. Int J Environ Res Public Health 2018; 15(7): 1410.
18.                Rouw R, Erfanian M. A large-scale study of misophonia. J Clin Psychol 2018; 74(3): 453-79.
19.                Dozier TH, Morrison KL. Phenomenology of misophonia: Initial physical and emotional responses. Am J Psychol 2017; 130(4): 431-8.
20.                Erfanian M, Kartsonaki C, Keshavarz A. Misophonia and comorbid psychiatric symptoms: A preliminary study of clinical findings. Nord J Psychiatry 2019; 73(4-5): 219-28.
21.                Schröder A, Vulink N, Denys D. Misophonia: Diagnostic criteria for a new psychiatric disorder. PLoS ONE 2013; 8(1): e54706.
22.                Jager I, de Koning P, Bost T, Denys D, Vulink N. Misophonia: Phenomenology, comorbidity and demographics in a large sample. PLoS ONE 2020; 15(4): e0231390.
23.                Gelder MG, Andreasen, NC, Lopez-Ibor JJ, Geddes JR. New Oxford .Textbook of Psychiatry. Oxford, UK:  Oxford University; 2012.