Introduction: Today, there is an increasing rate of coronary artery disease in different societies. The present study is aimed to compare between the aspects of perfectionism, cerebral-behavioral system, and resiliency in coronary artery patients versus normal individuals.
Materials and Methods: Sample of this causal-comparative research consisted of 300 individuals (150 patients and 150 healthyt individuals) admitted at Tehran cardiovascular hospitals in 2013. Convenient sampling was carried out. Research tool included Frost Multidimensional Perfectionism Scale (FMPS), Behavioral Inhibitory Systems-Behavioral Activating System scale (BIS/BAS) of Carver White, and Connor-Davidson Resiliency Scale (CD-RISC). Data analyzed by statistical values, logistic regression analysis, binominal test, and Mann-Whitney test through SPSS software version 18.
Results:Results indicated that there is positive significant relationship between the aspects of perfectionism (practical doubtfulness, parents’ expectations, and discipline) and standard variable (two conditions: patient and healthy) (P<0.05).  In brain/behavioral system, there is positive significant relationship between behavioral inhibition, escape, and activation with standard variable (P<0.05). Yet, resiliency had no significant difference between two groups (P=0.158).   
Conclusion: According to the results of the present research, specific components of perfectionism dimensions and systems of brain-behavior is  associated dedicated coronary heart disease and can be a useful component in the analysis of psychological are  of coronary heart disease.